Functional surfaces in microfluidic systems

Biological systems possess unique and evolutionary optimized properties that are of particular interest for areas of material science. One of these properties is the possibility of high-precision molecular recognition. In various diseases and metabolic disorders such as Alzheimer's and diabetes type II, this manifests itself in the pathological formation of peptide supramolecular structures, which become microscopically visible as amyloid deposits. The simulation of these formation processes in the laboratory and their simulation on the computer with the aim of using these molecular recognition mechanisms for the production of technically relevant systems on surfaces is anchored in the research focus "Hybrid bionanomaterials".

Three-dimensional microstructured polymer materials can be produced by self-organisation as well as by defined structuring processes. Radiation-chemical methods play a decisive role for both variants of production. Self-organisation is a basic principle which is used for the synthesis of porous and macroporous materials with a high surface/volume ratio. Such systems are suitable as drug carriers, filters or materials for regenerative medicine. Defined surface structures in polymer materials can be created by shaping. Radiation-chemical replications and so-called cryoprinting are processes that make it possible to realize multifunctional microsystem components in an application-oriented research environment.

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