Nanomedicine offers a variety of new applications in medical treatment and diagnostics. Nanoparticles are already used in rapid medical tests and assays and are promising drug components for tumor therapy. Here, especially the surface of the nanoparticles is of elementary importance for the subsequent application. Thus, the bio-compatibility, the toxicokinetics and the general suspendability of the particles are determined by the surface functionality. Targeted surface functionalization and tuning of sensory properties of nanoparticles is the central topic of the "Biosensory Nanoparticles and Surfaces" topic. Our expertise is in the synthesis of luminescent nano- and macromolecular systems using electron- and photon-based synthesis strategies. These will be used to fabricate selective optical sensing devices for medical applications. Such tailored nanoparticles find application in the fields of tumor therapy, tumor diagnostics and tissue diagnostics.